The Pathology Core and Lab was created to support the research and clinical activities of the Breast Center at Baylor College of Medicine.
We provide pathology-related services to the faculty and collaborators of the Smith Breast Center. Our lab members include pathologists specialized in breast diseases (human and animal models) and the management of clinical and research-oriented laboratories, as well as highly trained and experienced histology and research technicians. The resources include 1,500 square feet of new laboratory space, modern equipment to support all aspects of routine histotechnology, and additional instruments for specialized technologies such as automated immunohistochemistry, quantitative image analysis, laser-capture microdissection, fluorescent microscopy, confocal microscopy, and tissue microarrays.
Pathology Consultation
One of our experienced pathologists will sit with you to review your slides.
Clinical Services
The primary clinical services provided by the Pathology Laboratory include the diagnostic evaluation of breast biopsies/excisions and assessment of prognostic/predictive biomarkers in breast cancers (e.g. ER, PR, erbB2, and Ki67).
Research Services
The primary research support provided by the Pathology Laboratory includes routine histology, immunohistochemistry, and consultation/collaboration with pathologists. Immunohistochemistry is a particular strength, with assays developed for over 200 antibodies against important cancer-related molecules, and a systematic approach of developing assays for new antibodies with a high rate of success. The laboratory also works very closely with the Breast Tissue/Tumor Bank of the Smith Breast Center, which, together, provides investigators with appropriate samples for their research.
All services offered by the Pathology Laboratory are supported by the Breast Center and a variety of research grants awarded to its faculty, including one of only nine Specialized Programs of Research Excellence (SPORE) in Breast Cancer granted by the National Institute of Health.
Dr. Carolina Gutierrez - Core Director
Email: mgutierr@bcm.edu
Dr. Alejandro Contreras - Co-Director
Email: alejandr@bcm.edu
Contact Persons:
Rena Mao - smao@bcm.edu
Joy Guo - zguo@bcm.edu
Robin Sample - Administrator
Email: pathcore@breastcenter.tmc.edu
Phone: 713-798-1629
Location |
Hours |
Breast Center Pathology Core & Lab One Baylor Plaza, BMC-600 Houston, TX 77030 |
8 a.m. - 5 p.m., M - F
|
Name | Role | Phone | Location | |
---|---|---|---|---|
Dr. George Miles |
Director
|
713-798-1646
|
George.Miles@bcm.edu
|
BMC-600
|
Rena Mao |
smao@bcm.edu
|
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Breast Center Pathology |
Contact
|
713-798-1646
|
pathcore@breastcenter.tmc.edu
|
|
Internal BCM iLab Support |
Internal BCM iLab Support
|
ilabs-support@bcm.edu
|
Services & Costs |
► Consulting (1) | |||
Name | Description | Price | |
---|---|---|---|
Pathologist Read of Slide (per slide) | Inquire | ||
► Mass Spectrometery Services (3) | |||
Name | Description | Price | |
Mass Spectrometry Data Analysis |
Processing raw data into protein data frames. |
Inquire | |
Mass Spectrometry Sample Analysis |
Instrument utilization per hour. |
Inquire | |
Mass Spectrometry Sample Processing |
Custom tailored sample processing (this request includes reagents, SSO and labor). |
Inquire | |
► Microtomy (3) | |||
Name | Description | Price | |
Microtomy, Frozen sections | Inquire | ||
Microtomy, Paraffin sections | Inquire | ||
Paraffin (tissue array) sections | Inquire | ||
► Processing and Embedding (8) | |||
Name | Description | Price | |
Cells, fixed to paraffin block | Inquire | ||
Cells, unfixed to paraffin block | Inquire | ||
Processing Only | Inquire | ||
Re-embed / re-orient Paraffiin block | Inquire | ||
Tissue, fixed to paraffin block | Inquire | ||
Tissue, unfixed for freezing in storage tube | Inquire | ||
Tissue, unfixed for freezing to OCT Block | Inquire | ||
Tissue, unfixed to paraffin block | Inquire | ||
► Special Procedures (26) | |||
Name | Description | Price | |
Apoptosis Assay - IHC | Inquire | ||
Assay Development - IHC | Inquire | ||
Blood processing/fractionation (1 tube) | Inquire | ||
Blood Processing/Fractionation - Additional Tube Fee | Inquire | ||
DNA Cleaner/Concentrator - Zymo | Inquire | ||
DNA extraction-Blood/buffy coat/PBMC | Inquire | ||
DNA extraction-FFPE tissue | Inquire | ||
DNA extraction-Oragene Saliva | Inquire | ||
DNA extraction-PAXgene DNA | Inquire | ||
DNA Quantification - NanoDrop | Inquire | ||
DNA Quantification - PicoGreen-Qubit | Inquire | ||
Laboratory services (lab personnel time) | Inquire | ||
PBMC specimen processing (1 tube) | Inquire | ||
PBMC specimen processing (1 tube) - Addtl Tube Fee | Inquire | ||
Sample Processing Expedite Fee | Inquire | ||
Sample Retrieval | Inquire | ||
Sample storage (-20°C or -80°C freezer) | Inquire | ||
Special processes for FFPE/frozen tissues |
Sectioning and placement on pre-printed specialty slides (i.e. spatial transcriptomics) |
Inquire | |
Study Start-up Fee | Inquire | ||
TMA, beecher 0.6 mm - 100 cores | Inquire | ||
TMA, beecher 0.6 mm - 200 cores | Inquire | ||
TMA, manual 2 mm - 54 cores | Inquire | ||
TMA, manual 3 mm - 30 cores | Inquire | ||
TMA, manual 4 mm - 20 cores | Inquire | ||
TMA, manual 5 mm - 12 cores | Inquire | ||
TMA, manual 6 mm - 12 cores | Inquire | ||
► Staining Procedures (7) | |||
Name | Description | Price | |
BRDU Staining | Inquire | ||
Florescence one antibody | Inquire | ||
Florescence three antibody | Inquire | ||
Florescence two antibody | Inquire | ||
H and E Slide | Inquire | ||
IHC (Core supplied antibody) | Inquire | ||
IHC (investigator supplied antibody) | Inquire |