About

Advanced Cell Engineering and 3D Models Core

 

Overview of Services

Welcome to the Advanced Cell Engineering and 3D Models Core at Baylor College of Medicine.

 

Continuing the tradition of innovative collaboration with Baylor College of Medicine, the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation has generously donated $2.26 million to enable the establishment of the Cell-Based Assay Screening Service (C-BASS) core facility, housed in the Verna and Marrs McLean Department of Biochemistry and Molecular Biology.  By providing access to professional expertise and a variety of cutting-edge technologies and robotics platforms, the C-BASS core facility seeks to facilitate the advancement of our understanding of complex biological questions using well-established model systems, and to foster collaborations amongst BCM researchers.

 

The three major platforms are RNAi-mediated functional genomics, BiFC-based protein-protein interaction studies, and CRISPR/Cas9-mediated genome editing.

The C-BASS core houses several genomic libraries, including human and mouse shRNA and cDNA library collections. shRNA/cDNA clones are provided individually, in arrayed format, or as pools.  The automated instruments in the core facilitate the use of these reagents in screens and in studies of specific pathways or individual genes.

 

 

 

Services and Resources:

  • Human and mouse GIPZ shRNA and cDNA library collections, for a nominal fee to cover handling and storage costs
  • CRISPR/Cas9-mediated genome-editing services
  • Target-based shRNA libraries or druggable genome collections
  • Lentiviral packaging and stable cell line genereation
  • Automated liquid handling such as cherry-picking and DNA prepping in 96-well format

Read core guidelines and use the online forms on the Request Services tab to get started. (One-time registration is required to set up your account.)

 Please send all inquiries to cbasscore@bcm.edu

 

Getting Started

 

  • BCM Users:  Click the link in the upper right corner to login or register for an iLab account using valid BCM credentials.

 

  • Non-BCM Users:  Click the appropriate link in the upper right corner to login with your approved iLab credentials or to sign up for an iLab account.

 

 

  

Leadership

Hugo Villanueva, Ph.D.

Email: hugov@bcm.edu

Tel: (713) 798-0118

Jun Xu, Ph.D.

Email: junx@bcm.edu

Tel: (713) 798-8987

Fax: (713) 796-9438

 

Location and Hours of Operation

Location

 Hours

Advanced Cell Engineering and 3D Models Core

Room T143, One Baylor Plaza,

Baylor College of Medicine, Houston, TX 77030

Phone:  713-798-8987

Fax:  713-796-9438

email: ATC-ACE3MCore@bcm.edu

9 a.m. - 5 p.m., Monday to Friday

 

 

 

Links and Resources

 Visit our BCM core website for additional information.

  

Publication Acknowledgements

 

Scientific publications containing data obtained using the services offered by the core should include the following statement in the acknowledgment section: This project was supported by the Advanced Cell Engineering and 3D Models Core at BCM.

 

Contacts

Name Role Phone Email Location
Hugo Villanueva
Director
 
713-798-0118
 
hugov@bcm.edu
 
Room T143
 
Jun Xu
Director
 
713-798-8987
 
junx@bcm.edu
 
Room T143
 
Internal BCM iLab Support
Internal BCM iLab Support
 

 
ilabs-support@bcm.edu
 

 

Price Schedule


Search available services: View: by category alphabetically
► CRISPR Cloning Services (2)
► CRISPR KO Cell Line Services (1)
► shRNA / cDNA Library Collections (6)
► Lentiviral Stocks (2)
► Other (2)